Mepolizumab

Therapeutic value No judgement
Total cost 1,971,022,500.00
Registration phase Unknown
ATMP Unknown

Product

Active substance Mepolizumab
Domain Lung diseases
Main indication COPD
Extended indication COPD
Proprietary name Nucala
Manufacturer GSK
Route of administration Subcutaneous
Therapeutical formulation Injection
Budgetting framework Intermural (MSZ)
Additional comments Al geregistreerd voor astma.

Registration

Registration route Centralised (EMA)
Expected Registration 2018
Orphan drug No
Additional comments Indicatie-uitbreiding

Therapeutic value

Substantiation Wordt off-label al voorgeschreven.
Duration of treatment Not found
Frequency of administration 1 times a month
Dosage per administration 100 mg

Expected patient volume per year

Patient volume

5,000 - 250,000

Market share is generally not included unless otherwise stated.

Expected cost per patient per year

Cost < 15,459.00
References Medicijnkosten.nl
Additional comments Meerkosten. per injectieflacon van 100mg fl € 1263,52. Komt bovenop huidige kosten.

Potential total cost per year

Total cost

1,971,022,500.00

This amount gives an indication of the total cost. It is the result of the average expected patient volume times the average cost per patient. both per year.

Off label use

Off label use Yes
Indications off label use Gezien lastige indicatiestelling - grote kans op off-label gebruik.

Indication extension

Indication extension Yes
Indication extensions Meerdere fase 3 studies

Other information

There is currently no futher information available.