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Published on 13 December 2018
Allergy
Antithrombotic medications
Asthma
Bacterial infections
Bladder cancer
Bowel diseases
Brain cancer
Breast cancer
COPD
Cardiovascular diseases
Cervical cancer
Colon cancer
Cystic fibrosis
Ivacaftor
Kalydeco granules are indicated for the treatment of children with cystic fibrosis (CF) aged 12-24 months and weighing 7 kg to less than 25 kg who have one of the following gating (class III) mutations in the CFTR gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N or S549R
IND
Cystische fibrose voor kinderen van 6 tot 12 maanden met een gating mutatie.
IND
Kalydeco tablets are indicated in a combination regimen with tezacaftor 100 mg/ivacaftor 150 mg tablets for the treatment of patients with cystic fibrosis (CF) aged 12 years and older who are homozygous for the F508del mutation or who are heterozygous for the F508del mutation and have one of the following mutations in the CFTR gene: P67L, R117C, L206W, R352Q, A455E, D579G, 711+3A→G, S945L, S977F, R1070W, D1152H, 2789+5G→A, 3272-26A→G, and 3849+10kbC→T.
Lumacaftor / ivacaftor
IND
Tezacaftor / ivacaftor
Symkevi is indicated in a combination regimen with ivacaftor 150 mg tablets for the treatment of patients with cystic fibrosis (CF) aged 12 years and older who are homozygous for the F508del mutation or who are heterozygous for the F508del mutation and have one of the following mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene: P67L, R117C, L206W, R352Q, A455E, D579G, 711+3A→G, S945L, S977F, R1070W, D1152H, 2789+5G→A, 3272-26A→G, and 3849+10kbC→T.
Cystische fibrose voor patiënten van 6 tot en met 11 jaar met met een dubbele F508del-mutatie of één F508del plus één van de volgende 14 mutaties: P67L, R117C, L206W, R352Q, A455E, D579G, 711+3A→G, S945L, S977F, R1070W, D1152H, 2789+5G→A, 3272-26A→G, 3849+10kbC→T.
IND
Dementia
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Epilepsy
Eye disorders
Graft versus Host
Head and neck cancer
Durvalumab / Tremelimumab
Headache
Hematology other
Hemostasis promoting medication
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