Tirzepatide Medicine 06 June 2023 Extended indication Extension of indication to include chronic weight management, including weight loss and weight maintenance, for MOUNJARO. Therapeutic value No estimate possible yet Total cost Registration phase Registration application pending Product Active substance Tirzepatide Domain Metabolism and Endocrinology Reason of inclusion Indication extension IND Main indication Other metabolism and Endocrinology Extended indication Extension of indication to include chronic weight management, including weight loss and weight maintenance, for MOUNJARO. Current proprietary name Already available biosimilars / generics Proprietary name Mounjaro Manufacturer Eli Lilly Portfolio holder Eli Lilly Mechanism of action Other, see general comments Route of administration Subcutaneous Therapeutical formulation Injection Budgetting framework Extramural (GVS) Centre of expertise Additional remarks Gecombineerde GIP/GLP-1 agonist. Tirzepatide is één enkel molecuul. Registration Registration route Centralised (EMA) Type of trajectory Unknown Particularity Unknown ATMP No Submission date March 2023 Expected Registration January 2024 Orphan drug No Registration phase Registration application pending Reimbursement Medicine sluice Additional remarks Therapeutic value Current treatment options Therapeutic value No estimate possible yet This assessment does not indicate any potential inclusion in the package. Substantiation Duration of treatment Frequency of administration Dosage per administration References Additional remarks Expected patient volume per year Patient volume Market share is generally not included unless otherwise stated. Maximum patient volume for sluice References Additional remarks Expected cost per patient per year Cost References https://www.farmacotherapeutischkompas.nl Additional remarks De kosten voor een 0,5 ml injectievloeistof bevattende Tirzepatide 10 mg/ml bedragen € 102,05. Potential total cost per year Total cost Total cost for sluice Additional remarks Off label use Off label use Unknown Indications off label use References Additional remarks Indication extension Indication extensions Unknown Indication extensions References Additional remarks Other information Additional remarks