MABp1 Medicine 09 January 2018 Extended indication Debilitating symptoms of advanced colorectal cancer Therapeutic value No judgement Total cost Registration phase Unknown Product Active substance MABp1 Domain Oncology and Hematology Reason of inclusion Main indication Unknown Extended indication Debilitating symptoms of advanced colorectal cancer Current proprietary name Already available biosimilars / generics Proprietary name Xilonix Manufacturer Xbiotech Portfolio holder Mechanism of action Unknown Route of administration Unknown Therapeutical formulation Unknown Budgetting framework Unknown Centre of expertise Additional remarks Negatieve CHMP opinie in mei 2017, bevestigd in september 2017. Registration Registration route Unknown Type of trajectory Unknown Particularity Unknown ATMP Unknown Submission date Expected Registration Orphan drug Unknown Registration phase Unknown Reimbursement Medicine sluice Additional remarks Therapeutic value Current treatment options Therapeutic value No judgement This assessment does not indicate any potential inclusion in the package. Substantiation Duration of treatment Frequency of administration Dosage per administration References Additional remarks Expected patient volume per year Patient volume Market share is generally not included unless otherwise stated. Maximum patient volume for sluice References Additional remarks Expected cost per patient per year Cost References Additional remarks Potential total cost per year Total cost Total cost for sluice Additional remarks Off label use Off label use Unknown Indications off label use References Additional remarks Indication extension Indication extensions Unknown Indication extensions References Additional remarks Other information Additional remarks