Mometasone furoate sinus drug depot Medicine 04 June 2024 Extended indication Chronic rhinosinusitis (CRS) patients who have had a prior functional endoscopic sinus surgery. Therapeutic value No estimate possible yet Total cost Registration phase Clinical trials Product Active substance Mometasone furoate sinus drug depot Domain Lung diseases Reason of inclusion New medicine (specialité) Main indication Lung diseases other Extended indication Chronic rhinosinusitis (CRS) patients who have had a prior functional endoscopic sinus surgery. Current proprietary name Already available biosimilars / generics Proprietary name Manufacturer Intas Portfolio holder Mechanism of action Unknown Route of administration Nasal Therapeutical formulation Unknown Budgetting framework Intermural (MSZ) Centre of expertise Additional remarks Werkingsmechaninsme: Glucocorticoid receptor agonist Registration Registration route Centralised (EMA) Type of trajectory Unknown Particularity Unknown ATMP No Submission date September 2024 Expected Registration October 2025 Orphan drug Unknown Registration phase Clinical trials Reimbursement Medicine sluice Additional remarks NCT05219968 Therapeutic value Current treatment options Therapeutic value No estimate possible yet This assessment does not indicate any potential inclusion in the package. Substantiation Duration of treatment Frequency of administration Dosage per administration 7500 µg References Additional remarks Expected patient volume per year Patient volume Market share is generally not included unless otherwise stated. Maximum patient volume for sluice References https://richtlijnen.nhg.org/standaarden/acute-rhinosinusitis#:~:text=De%20incidentie%20van%20rhinosinusitis%20(zowel,vaker%20voor%20dan%20bij%20mannen. Additional remarks De incidentie van rhinosinusitis (zowel acuut als chronisch) in de huisartsenpraktijk wordt geschat op 30 per 1.000 patiënten per jaar. Expected cost per patient per year Cost References Additional remarks Potential total cost per year Total cost Total cost for sluice Additional remarks Off label use Off label use Unknown Indications off label use References Additional remarks Indication extension Indication extensions Unknown Indication extensions References Additional remarks Other information Additional remarks