Longziekten algemeen

Astma

• Depemokimab

• Formoterol / glycopyronium / budesonide

  • Maintenance treatment of asthma in patients 12 years of age and older who are not adequately controlled by a combination of a medium or high dose inhaled corticosteroid and a long-acting beta2-agonist.

COPD

• Benralizumab

  • Moderate to very severe Chronic Obstructive Pulmonary Disease (COPD) with exacerbation history.

• Dupilumab

  • Add-on maintenance treatment for adults with uncontrolled chronic obstructive pulmonary disease (COPD) characterized by raised blood eosinophils for patients already on a combination of an inhaled corticosteroid (ICS), a long-acting beta2-agonist (LABA) and a long-acting muscarinic antagonist (LAMA), or on a combination of a LABA and a LAMA if ICS is not appropriate.
• Ensifentrine
• Itepekimab

• Mepolizumab

  • Extension of indication to include treatment of Chronic Obstructive Pulmonary Disease (COPD).
• Tozorakimab ^IND

Longziekten, overig

• Alpha-1 antitrypsin

• Benralizumab

  • Extension of indication to include treatment of eosinophilic granulomatosis.
• Brensocatib

• Ciclosporine

  • Ciclosporin in combination with standard therapy for the treatment of bronchiolitis obliterans syndrome in adults and the elderly after lung transplantation.
• Efzofitimod ^G
• Exoflo Extracellular Vesicles
• Nerandomilast

• Nintedanib

  • Ofev is indicated in children and adolescents aged 6 to 17 years for the treatment of clinically significant, progressive fibrosing interstitial lung diseases (ILDs).

• Riociguat

  • Adempas is indicated for the treatment of PAH in paediatric patients aged 6 to less than 18 years with WHO Functional Class (FC) II to III in combination with endothelin receptor antagonists (see section 5.1).

• Sotatercept

  • Treatment of pulmonary arterial hypertension.
  • Extension of indication to include in combination with other pulmonary arterial hypertension (PAH) therapies treatment of adult patients with PAH World Health Organisation Functional Class IV.

• Tezepelumab

  • Tezspire is indicated as an add-on therapy with intranasal corticosteroids for the treatment of adult patients with severe CRSwNP for whom therapy with systemic corticosteroids, and/or surgery do not provide adequate disease control.

• Treprostinil

  • Treprostinil monotherapy for treatment of idiopathic pulmonary fibrosis in adults over 40 years of age and elderly.

Onbekend

• ARINA-1
• Colistimethaatnatrium ^IND

Taaislijmziekte

• Ivacaftor / Tezacaftor / Elexacaftor ^IND
• Vanzacaftor / tezacaftor / deutivacaftor

Onbekend

• Tanimilast