ADHD Lisdexamfetamine IND Molindone ALS Arimoclomol Bipolar disorder Lumateperone Lurasidone IND Dementia Aducanumab Leuco-methylthioninium Alzheimer’s disease, mild-to-moderate. Dementia, behavioural variant frontotemporal. Depression Brexanolone Esketamine Spravato, in combination with a SSRI or SNRI, is indicated for adults with treatment-resistant major depressive disorder, who have not responded to at least two different treatments with antidepressants in the current moderate to severe depressive episode. Extension of indication to include a new indication for Spravato for the rapid reduction of depressive symptoms in adult patients with a moderate to severe depressive episode of MDD who have current suicidal ideation with intent. IND Zuranolone Duchenne Edasalonexent Idebenone Treatment of respiratory dysfunction in patients with Duchenne muscular dystrophy (DMD) NOT using glucocorticoids. Respiratory dysfunction is defined when PEF%p or FVC%p fall below 80% of the predicted value Treatment of respiratory dysfunction in patients with Duchenne muscular dystrophy (DMD) using glucocorticoids. Respiratory dysfunction is defined when PEF%p or FVC%p fall below 80% of the predicted value IND Epilepsy Cannabidiol Indicated for use as adjunctive therapy of seizures associated with Lennox‑Gastaut syndrome (LGS) or Dravet syndrome (DS), in conjunction with clobazam, for patients 2 years of age and older. Extension of indication for use as adjunctive therapy of seizures associated with tuberous sclerosis complex (TSC) for patients 1 year of age and older. IND Cenobamate Fenfluramine Fintepla is indicated for the treatment of seizures associated with Dravet syndrome as an add-on therapy to other anti-epileptic medicines for patients 2 years of age and older. Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome IND Perampanel IND Eye disorders Abicipar Aflibercept BS Aganirsen Brolucizumab IND Faricimab Latanoprostene bunod Lenadogene nolparvovec Lifitegrast Netarsudil / latanoprost Polihexanide Ranibizumab Wet age-related macular degeneration (AMD). BS Wet age-related macular degeneration (AMD). BS Wet age-related macular degeneration (AMD). BS Wet age-related macular degeneration (AMD). BS Treatment of neovascular age-related macular degeneration (AMD) Reproxalap Sepofarsen Timrepigene emparvovec Tivanisiran Voretigene neparvovec Headache Eptinezumab Erenumab Fremanezumab Galcanezumab Lasmiditan Hearing disorders Brimapitide Pioglitazone Multiple sclerosis Fampridine G Fingolimod G Masitinib Natalizumab Ofatumumab Ozanimod Ponesimod Siponimod Teriflunomide IND Muscular diseases Sugammadex G Other muscular diseases AMDC-USR Mexiletine HCl Other neurological disorders Buprenorphine Eculizumab IND Eladocagene exuparvovec Inebilizumab Remimazolam Ronopterin Satralizumab Pain Bupivacaine Bupivacaine / meloxicam Lidocaïne Neridronic Acid Tanezumab Treatment of moderate to severe chronic pain associated with OA of the hip or knee in adult patients for whom treatment with NSAIDs and/or any opioid is ineffective, not tolerated or inappropriate Chronic Low Back Pain for ≥3 months IND Parkinson's Amantadine Apomorphine Istradefylline Levodopa / carbidopa Pimavanserin SMA Onasemnogene abeparvovec Risdiplam Schizophrenia, psychosis Lurasidone IND Olanzapine / samidorphan Sleep disorders JZP-258 Lemborexant Natriumoxybaat IND Solriamfetol Tasimelteon IND