ADHD Lisdexamfetamine IND Molindone ALS Arimoclomol Bipolar disorder Lumateperone Dementia Aducanumab Leuco-methylthioninium Alzheimer’s disease, mild-to-moderate. Dementia, behavioural variant frontotemporal. Depression Brexanolone Bupropion/dextromethorphan Esketamine Spravato, in combination with a SSRI or SNRI, is indicated for adults with treatment-resistant major depressive disorder, who have not responded to at least two different treatments with antidepressants in the current moderate to severe depressive episode. Extension of indication to include a new indication for SPRAVATO® (esketamine nasal spray) co-administered with oral antidepressant therapy in adults with a moderate to severe episode of Major Depressive Disorder (MDD), as acute short term treatment, for the rapid reduction of depressive symptoms, which according to clinical judgement constitute a psychiatric emergency. IND Zuranolone Duchenne Golodirsen Epilepsy Brivaracetam IND Cannabidiol IND Cenobamate Fenfluramine Fintepla is indicated for the treatment of seizures associated with Dravet syndrome as an add-on therapy to other anti-epileptic medicines for patients 2 years of age and older. Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome IND Ganaxolone Lacosamide IND Perampanel IND Eye disorders Aflibercept BS Aganirsen Avacincaptad pegol Bevacizumab-vikg Brolucizumab IND Faricimab Latanoprostene bunod Lenadogene nolparvovec Netarsudil / latanoprost Perfluorohexyloctane Polihexanide Ranibizumab Wet age-related macular degeneration (AMD). BS Wet age-related macular degeneration (AMD). BS Wet age-related macular degeneration (AMD). BS Wet age-related macular degeneration (AMD). BS Treatment of neovascular age-related macular degeneration (AMD) Reproxalap Sepofarsen Timrepigene emparvovec Voretigene neparvovec Headache Eptinezumab Erenumab Fremanezumab Galcanezumab Lasmiditan Meloxicam/rizatriptan Rimegepant Hearing disorders Brimapitide Pioglitazone Multiple sclerosis Diroximel fumarate Fampridine G Fingolimod G Masitinib Natalizumab Ofatumumab Ponesimod Siponimod Teriflunomide IND Muscular diseases Bidridistrogene xeboparvovec Sugammadex G Other muscular diseases AMDC-USR Mexiletine HCl Other neurological disorders Cannabidiol gel/intradermaal Eladocagene exuparvovec Inebilizumab Remimazolam Ronopterin Satralizumab Tiratricol Other psychiatry Dexmedetomidine Pain Bupivacaine Bupivacaine / meloxicam Fasinumab Lidocaïne Neridronic Acid SDN037 Tanezumab Treatment of moderate to severe chronic pain associated with OA of the hip or knee in adult patients for whom treatment with NSAIDs and/or any opioid is ineffective, not tolerated or inappropriate Chronic Low Back Pain for ≥3 months IND Parkinson's Amantadine Apomorphine Istradefylline Levodopa / carbidopa SMA Onasemnogene abeparvovec Risdiplam Schizophrenia, psychosis Lurasidone IND Olanzapine / samidorphan Sleep disorders Daridorexant JZP-258 Lemborexant Natriumoxybaat IND Natriumoxybaat controlled release Pitolisant IND Tasimelteon IND