Neurologische aandoeningen

ALS

• Masitinib

Dementie

• Leuco-methylthioninium

  • Alzheimer’s disease, mild-to-moderate.
  • Dementia, behavioural variant frontotemporal.

Epilepsie

• Cannabidiol
• Fenfluramine
• Vigabatrin

Hoofdpijn

• Eptinezumab
• Erenumab
• Fremanezumab

• Galcanezumab

  • Emgality is indicated for the prophylaxis of migraine in adults who have at least 4 migraine days per month.
  • Clusterhoofdpijn^IND
• Lasmiditan

Multiple sclerose

• ALKS8700
• Biotin
• Cladribine
• Fingolimod^IND
• Masitinib

• Ocrelizumab

  • Volwassen patiënten met actieve relapsing multiple sclerose (RMS) die is gedefinieerd door klinische of beeldvormende kenmerken.
  • Volwassen patiënten met vroege primair progressieve multiple sclerose (PPMS) gebaseerd op de ziekteduur, mate van invaliditeit en beeldvormende kenmerken die typerend zijn voor ontstekingsactiviteit.
• Ozanimod
• Siponimod

Neurologie overig

• Botulinum A toxin^IND
• Brimapitide
• Buprenorphine
• CM-AT / CM-4612
• Esketamine
• Inotersen
• Natriumoxybaat
• Patisiran
• Ronopterin

Oogaandoeningen

• Abicipar
• Aflibercept^BS
• Aganirsen
• Brolucizumab
• Cenegermin

• Ciclosporin

  • Treatment of severe vernal keratoconjunctivitis in children from 4 years of age and adolescents.
  • Keratoconjunctivitis sicca (or dry eye disease), moderate-to-severe and specifically in patients with atopic keratoconjunctivitis.

• KPI-121

  • Ocular pain and inflammation. Om te gebruiken na oogchirurgie.
  • Dry eye disease.
• Latanoprostene bunod
• Lenadogene nolparvovec
• Lifitegrast
• Netarsudil mesylate
• Polihexanide

• Ranibizumab

  • Wet age-related macular degeneration (AMD).^BS
  • Wet age-related macular degeneration (AMD).^BS
  • Wet age-related macular degeneration (AMD).^BS
  • Wet age-related macular degeneration (AMD).^BS
• Reproxalap
• RGN-259
• Voretigene neparvovec

Parkinson

• Apomorphine
• Ioflupane (123I)^G
• Levodopa
• Pimavanserin

Pijn

• Neridronic Acid
• Oxycodon ER

Psychiatrie

• Brexanolone
• Brexpiprazole

• Cariprazine

  • Schizofrenie bij volwassenen.
  • Bipolaire depressie
• Cariprazine (hydrochloride)

• Esketamine

  • Treatment resistant depression (Major Depressive Disorder in adults who have not responded to at least two different treatments with antidepressants in the current moderate to severe depressive episode)
  • Major Depressive Disorder with imminent risk of suicide^IND
• Lurasidone^IND

Slaapstoornissen

• Lemborexant
• Melatonin
• Natriumoxybaat^IND
• Pitolisant^IND
• Solriamfetol

• Tasimelteon

  • Jet lag disorder^IND
  • Behandeling van volledig blinde volwassenen met niet-24-uurs slaap-waakstoornis (N24HSWD).

Spierziekten

• Adeno-associated viral vector serotype 9 containing the human SMN gene (AVXS-101)
• AMDC-USR

• Botulinum A toxin

  • Lower limb spasticity (LLS), in adults post stroke or traumatic brain injury (TBI).^IND
  • Treatment of adult patients with glabellar lines, also known as "frown lines" between the eyebrows.
  • Lower limb spasticity (LLS), post stroke.
• Eculizumab
• Edaravone
• Eteplirsen
• Ibudilast
• Idebenone
• Mexiletine HCl
• Nusinersen
• Onasemnogene abeparvovec
• Valbenazine