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Chronic immune diseases
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Mechanism of action
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PARP inhibitor
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Budgetting framework
Any budgetting framework
Unknown
Extramural (GVS)
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Particularity
Any particularity
Unknown
New medicine with Priority Medicines (PRIME)
New therapeutical formulation
Reason of inclusion
New medicines
Indication extensions
IND
Biosimilars / generics
BS
G
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Bowel diseases
Apraglutide
Etrasimod
Glepaglutide
Guselkumab
Tremfya is indicated for the treatment of adult patients with moderately to severely active Crohn’s disease who have had an inadequate response, lost response, or were intolerant to either conventional therapy or a biologic treatment.
IND
Tremfya is indicated for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response, lost response, or were intolerant to either conventional therapy, or a biologic treatment.
IND
Hydrocortison
IND
Ivarmacitinib
Mirikizumab
IND
Obefazimod
IND
Risankizumab
IND
Teduglutide
BS
Ustekinumab
IND
Cardiovascular diseases
Secukinumab
IND
Eye disorders
Veligrotug
Other chronic immune diseases
13-grass pollen extract
Allergeenextract huisstofmijt
IND
Arachis hypogaea (pinda) allergenen
IND
Atrasentan
Briquilimab
Budesonide
IND
Coacillium topical
Donidalorsen
Dupilumab
Dupixent is geïndiceerd voor de behandeling van eosinofiele oesofagitis in volwassenen, adolescenten en kinderen van 1 jaar en ouder. Die ongecontroleerd zijn op, intolerant zijn voor, of die geen kandidaat zijn voor conventionele therapie.
IND
Extension of indication to include treatment of moderate to severe chronic spontaneous urticaria in adults and adolescents 12 years and older, whose disease is inadequately controlled by H1 antihistamines and who are naive to anti-IgE therapy for CSU.
IND
Epinephrine
Garadacimab
Imlifidase
IND
Iptacopan
IND
Lanalumab
Leniolisib
Lorecivivint
Marnetegragene autotemcel
Masitinib
Mavorixafor
Mycofenolaatmofetil
IND
Obinutuzumab
IND
Pegcetacoplan
IND
Ritlecitinib
Sarilumab
IND
Sebetralstat
Secukinumab-bthr
BS
Sibeprenlimab
Upadacitinib
Moderate to severe Hidradenitis suppurativa in adolescents, adults and elderly who have failed to respond to or are intolerant of anti-tumor necrosis factor (TNF) therapy.
IND
Severe Alopecia areata in adolescents and adults.
IND
Rheumatism
Anifrolumab
Bimekizumab
Bimzelx is indicated for the treatment of adults with active non-radiographic axial spondyloarthritis with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI) who have responded inadequately or are intolerant to non-steroidal anti-inflammatory drugs (NSAIDs), and for the treatment of adults with active ankylosing spondylitis who have responded inadequately or are intolerant to conventional therapy.
IND
Bimzelx, alone or in combination with methotrexate, is indicated for the treatment of active psoriatic arthritis in adults who have had an inadequate response or who have been intolerant to one or more disease-modifying antirheumatic drugs (DMARDs).
IND
Dapansutrile
Emapalumab
Filgotinib
IND
Golimumab
BS
Inebilizumab
IND
Ixekizumab
IND
Lingolinurad
Litifilimab
Sarilumab
IND
Secukinumab
IND
Upadacitinib
IND
Skin diseases
Afamelanotide
IND
Apremilast
IND
Beremagene geperpavec
Bimekizumab
IND
Clascoterone
Dabocemagene autoficel
Deuruxolitinib
Dipalmitoyl Hydroxyproline
Dupilumab
IND
Guselkumab
IND
Imsidolimab
Lebrikizumab
Ebglyss is indicated for the treatment of moderate-to-severe atopic dermatitis in adults and adolescents 12 years and older with a body weight of at least 40kg who are candidates for systemic therapy.
Lebrikizumab in combination with topical corticosteroid for treatment of moderate to severe atopic dermatitis in infants, toddlers over 6 months, children and adolescents.
IND
Nemolizumab
Piclidenoson
Prademagene zamikeracel
Remibrutinib
Risankizumab
IND
Roflumilast topicaal
IND
Ruxolitinib (als fosfaat)
Volwassenen met matige atopische dermatitis die eerder zijn behandeld met topische corticosteroïden of topische calcineurine remmers of waarbij deze middelen zijn gecontra-indiceerd.
IND
Prurigo nodularis (PN)
IND
Tildrakizumab
Tildrakizumab monotherapy for treatment of active Psoriatic arthritis in adults and elderly who have no prior exposure to anti-tumor necrosis factor agent.
Tildrakizumab monotherapy for treatment of active psoriatic arthritis in adults and elderly who have prior exposure to anti-tumor necrosis factor agent.
Tirbanibulin
Tirbanibuline
IND
Upadacitinib
IND
Unknown
Atacicept
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