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Published on
4 June 2024
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Mechanism of action
Any mechanism of action
Unknown
Alkylating agent
Allergen
Allogeneic modified cell therapy
Amino acid
Anesthetic
Angiogenesis inhibitor
Antiandrogen
Antibiotic
Antibody-drug conjugate
Anticoagulant
Antifungals
Antihistamine
Antioxidant
Antisense oligonucleotide
Autologous modified cell therapy
Bcl-2 inhibitor
BET inhibitor
Calcineurin inhibitor
Cancer vaccine
Cannabinoid
CAR-T therapy
CDK4 / 6 tyrosine kinase inhibitor
CFS1R inhibitor
CGRP-directed antibody
Chelating agent
Coagulant
Combination therapy
Complement inhibitor
Corticosteroid
CTLA-4 antibody
Cytostatic
Disinfectant
Enzyme
Enzyme inhibitor
Enzyme replacement therapy
Gene therapy
GLP-1 receptor agonist
Glucagon analogue
Growth factor
HIV inhibitor
Hormonal therapy
Immunostimulation
Immunosuppression
Insulin preparation
Interferon inhibitor
Interleukin inhibitor
Ion channel blocker
JAK tyrosine kinase inhibitor
LABA / ICS
LABA / LAMA
LABA / LAMA / ICS
LAMA
MEK kinase inhibitor
Neurotoxin
Neurotransmitter
Oncolytic adenovirus
Other
Other, see general comments
PARP inhibitor
PD-1 / PD-L1 inhibitor
Proteasome inhibitor
Protein chaperone
Receptor agonist
Receptor antagonist
Serine / threonine kinase inhibitor
SGLT inhibitor
Small interfering RNA (siRNA)
Sodium channel blocker
Thrombin inhibitor
TNF-alpha inhibitor
Tyrosine kinase inhibitor
Vasodilator
Virus inhibitor
Budgetting framework
Any budgetting framework
Unknown
Extramural (GVS)
Intermural (MSZ)
Particularity
Any particularity
Unknown
New medicine with Priority Medicines (PRIME)
New therapeutical formulation
Reason of inclusion
New medicines
Indication extensions
IND
Biosimilars / generics
BS
G
Download
ADHD
Guanfacine
G
ALL
ARI-0001
Blinatumomab
IND
Brexucabtagene autoleucel
IND
Crisantaspase
Obecabtagene autoleucel
Ponatinib
IND
ALS
Ibudilast
Masitinib
Pridopidine
Reldesemtiv
Tofersen
AML / MDS
Decitabine / cedazuridine
Imetelstat
Ivosidenib
Luspatercept
IND
Magrolimab
Olutasidenib
Quizartinib
Aggressive non-Hodgkin’s lymphoma
Acalabrutinib
IND
Axicabtagene ciloleucel
IND
Brentuximab vedotin
Extension of indication to include in combination with cyclophosphamide, doxorubicin, and prednisone (CHP) treatment of adult patients with previously untreated CD30+ peripheral T-cell lymphoma not otherwise specified (PTCL-NOS).
IND
Extension of indication for ADCETRIS to include treatment for adult patients with previously untreated CD30+ Stage IIB with risk factors, Stage III or Stage IV HL in combination with etoposide, cyclophosphamide, doxorubicin, dacarbazine, dexamethasone.
IND
Epcoritamab
Glofitamab
Ibrutinib
IND
Lisocabtagene maraleucel
IND
Loncastuximab tesirine
Odronextamab
Pirtobrutinib
Polatuzumab vedotin
IND
Tafasitamab
Zamtocabtagene autoleucel
Antithrombotic medications
Apixaban
IND
Dabigatran
G
Tenecteplase
IND
Asthma
Depemokimab
Tezepelumab
Bacterial infections
Aztreonam / avibactam
Bezlotoxumab
IND
Ceftazidime / avibactam
IND
Durlobactam / sulbactam
Faecal microbiota transplant
Gepotidacin
Peginterferon alfa-2a
IND
Ridinilazole
Vonoprazan
Bladder cancer
Abnobaviscum 900
G
Durvalumab
IND
Enfortumab vedotin
IND
Erdafitinib
Inbakicept
Nivolumab
Extension of indication to include in combination with cisplatin-based chemotherapy the first-line treatment of adult patients with unresectable or metastatic urothelial carcinoma.
IND
OPDIVO in combination with cisplatin-based chemotherapy is indicated for the first-line treatment of adult patients with unresectable or metastatic urothelial carcinoma.
IND
Sacituzumab Govitecan
IND
Sasanlimab
Bowel diseases
Etrasimod
Glepaglutide
Guselkumab
Tremfya is geïndiceerd voor de behandeling van volwassen patiënten met matig tot ernstig actieve ziekte van Crohn die onvoldoende hebben gereageerd op, niet meer reageren op of intolerant waren voor conventionele behandeling of een biologische behandeling.
IND
Tremfya is geïndiceerd voor de behandeling van volwassen patiënten met matig tot ernstige colitis ulcerosa die onvoldoende hebben gereageerd op, niet meer reageren op of intolerant waren voor conventionele behandeling of een biologische behandeling.
IND
Mirikizumab
Omvoh is indicated for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response with, lost response to, or were intolerant to either conventional therapy or a biologic treatment
Crohn's disease
IND
Obefazimod
IND
Risankizumab
IND
Upadacitinib
IND
Brain cancer
Dabrafenib / trametinib
Paclitaxel trevatide
Vorasidenib
Breast cancer
Atezolizumab
IND
Camizestrant
Capivasertib
Datopotamab deruxtecan
Datopotamab deruxtecan as monotherapy is indicated for the treatment of adult patients with locally recurrent inoperable or metastatic Triple-Negative Breast Cancer (TNBC) who are not candidates for PD-1/PD-L1 inhibitor therapy.
IND
Datopotamab deruxtecan as monotherapy is indicated for the treatment of adult patients with inoperable or metastatic HR-Positive, HER2-negative Breast Cancer who have been treated with one or two prior lines of systemic chemotherapy.
IND
Elacestrant
Inavolisib
IND
Olaparib
IND
Paclitaxel
Palbociclib
IND
Ribociclib
IND
Sacituzumab govitecan
IND
Trastuzumab deruxtecan
Enhertu as monotherapy is indicated for the treatment of adult patients with unresectable or metastatic HER2 positive breast cancer who have received two or more prior anti HER2 based regimens.
Enhertu as monotherapy is indicated for the treatment of adult patients with unresectable or metastatic HER2‑low breast cancer who have received prior chemotherapy in the metastatic setting or developed disease recurrence during or within 6 months of completing adjuvant chemotherapy
IND
Extension of indication for Enhertu to include treatment of adult patients with unresectable or metastatic HER2-positive breast cancer who have received one or more prior anti-HER2-based regimens.
IND
Extension of indication to include treatment of HER2-low/ultra-low hormone receptor positive breast cancer patients whose disease has progressed on endocrine therapy in the metastatic setting.
IND
Vepdegestrant
CLL
Acalabrutinib
IND
Iopofosine I 131
Pirtobrutinib
IND
Zanubrutinib
Extension of indication to include treatment of adult patients with chronic lymphocytic leukaemia (CLL).
IND
Extension of indication to include treatment of adult patients with marginal zone lymphoma (MZL) who have received at least one-prior anti-CD20-based therapy
IND
CML
Bosutinib
IND
COPD
Dupilumab
IND
Ensifentrine
COVID-19
Casirivimab / imdevimab
Extension of indication to include treatment of COVID-19 in adults and adolescents aged 12 years and older weighing at least 40kg and receiving supplemental oxygen, who have a negative SARS-CoV-2 antibody test result.
IND
Extension of indication to include treatment of paediatric patients from 2 to less than 12 years old, weighing at least 10kg, who do not require supplemental oxygen and who are at increased risk of progression to severe COVID-19 for Ronapreve
IND
Sabizabulin
Vilobelimab
Cervical cancer
Cadonilimab
Dostarlimab
IND
Olaparib
IND
Tisotumab vedotin
Colon cancer
Fruquintinib
Nivolumab
IND
Pembrolizumab / favezelimab
Trifluridine / tipiracil
IND
Cystic fibrosis
Ivacaftor / Tezacaftor / Elexacaftor
IND
Lumacaftor / ivacaftor
IND
Vanzacaftor
Dementia
Blarcamesine
Donanemab
Lecanemab
NE3107
Depression
Agomelatine
IND
Zuranolone
Diabetes
Dasiglucagon
Deudomperidone
Empagliflozine
IND
Insulin Icodec
Insulin oral
Regulatoire T-cellen (TREGS)
Teplizumab
Duchenne
Fordadistrogene movaparvovec
Givinostat
Losmapimod
Vamorolone
Viltolarsen
Epilepsy
Diazepam nasaal
Ganaxolone
Eye disorders
Avacincaptad pegol
Bevacizumab-vikg
Bimatoprost
Botaretigene sparoparvovec
Brimonidine tartrate/carbachol
Faricimab
IND
Laruparetigene zosaparvovec
Pegcetacoplan
IND
Phentolamine
Polihexanide
Ranibizumab
Tarcocimab tedromer
Varenicline
Veligrotug
Fungal infections
Olorofim
Rezafungin
Graft versus Host
Axatilimab
Mc0518
HIV
Dolutegravir/ abacavir /lamivudine
IND
Semzuvolimab
Head and neck cancer
Atezolizumab
IND
Leukocyte interleukin
Tislelizumab
IND
Xevinapant
Headache
Atogepant
Hemostasis promoting medication
Emicizumab
IND
Etranacogene dezaparvovec
Fidanacogene elaparvovec
Turoctocog alfa pegol
IND
Valoctocogene roxaparvovec
Vonicog alfa
IND
Hodgkin's lymphoma
Brentuximab vedotin
Indolent non-Hodgkin’s lymphoma
Epcoritamab
IND
Lacutamab
Tafasitamab
IND
Zanubrutinib
IND
Infectious diseases other
Cefepime / Enmetazobactam
Cefepime/taniborbactam
Kidney cancer
Abexinostat
Belzutifan
Cabozantinib
IND
Lipid-lowering medications
Alirocumab
IND
Evinacumab
Extension of indication to include the treatment of paediatric patients with homozygous familial hypercholesterolaemia (HoFH) aged 5 years and older
IND
Extension of indication for EVKEEZA to include the treatment of paediatric patients with homozygous familial hypercholesterolaemia aged 6 months to less than 5 years
IND
Lomitapide
IND
Pravastatine/fenofibraat
IND
Liver cancer
Atezolizumab
IND
Durvalumab
Durvalumab (+/- bevacizumab) in combinatie met TACE in patiënten met locoregionale HCC.
IND
Imfinzi as monotherapy is indicated for the first line treatment of adults with advanced or unresectable hepatocellular carcinoma (HCC).
IND
Namodenoson
Tremelimumab
Liver diseases
Arachidyl amido cholanoic acid
Elafibranor
Maralixibat
Treatment of cholestatic pruritus in patients with Alagille syndrome (ALGS) 2 months of age and older.
Extension of indication to include treatment of Progressive Familial Intrahepatic Cholestasis (PFIC) in patients 3 months of age and older
IND
Obeticholic acid
Odevixibat
IND
Resmetirom
Seladelpar
Lung cancer
Adagrasib
Alectinib
IND
Amivantamab
Amivantamab in combination with carboplatin and pemetrexed for the first‑line treatment of adult patients with advanced non-small cell lung cancer (NSCLC) with activating EGFR Exon 20 insertion mutations.
IND
Amivantamab in combination with chemotherapy is indicated for the treatment of adult patients with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC) after osimertinib failure.
IND
Amivantamab in combination with lazertinib is indicated for the treatment of adult patients with epidermal growth factor receptor (EGFR) mutation (Exon 19 deletions [Exon 19del] or Exon 21 L858R substitution) positive, locally advanced or metastatic non-small cell lung cancer (NSCLC).
IND
Atezolizumab
Subcutaneous formulation of atezolizumab for treatment of PD-(L)-1 Cancer Immunotherapy in multiple tumor types.
IND
Extension of indication to include first-line treatment of adult patients with non-small cell lung cancer (NSCLC) who are ineligible for platinum-based chemotherapy and who do not have EGFR mutant or ALK-positive disease, who have: locally advanced unresectable NSCLC not amenable for definitive chemoradiotherapy, or metastatic NSCLC.
IND
Aumolertinib (mesilate)
Cobolimab
Datopotamab deruxtecan
Datopotamab deruxtecan, in combination with Pembrolizumab, is indicated for the treatment of adult patients with advanced or metastatic NSCLC without actionable genomic alterations whose tumor has high programmed death-ligand 1 (PD-L1) expression (tumor proportion score; TPS ≥50%) and who have not previously received systemic therapy for advanced or metastatic NSCLC.
IND
Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer, who have received at least one systemic therapy
Domvanalimab
Durvalumab
Lokaal gevorderd, niet-resectabel NSCLC (stadium III)
IND
1L advanced NSCLC
IND
Limited stage small cell lung cancer (LS-SCLC) following concurrent platinum-based chemotherapy and radiation therapy in combination with Tremelimumab.
IND
Extension of indication to include IMFINZI in combination with platinum-based chemotherapy as neoadjuvant treatment, followed by IMFINZI as monotherapy after surgery, for the treatment of adults with resectable (tumours ≥ 4 cm and/or node positive) NSCLC and no known EGFR mutations or ALK rearrangements.
IND
Encorafenib
IND
Ipilimumab
IND
Lazertinib
Lenvatinib
IND
Nintedanib
G
Nivolumab
OPDIVO in combination with platinum-based chemotherapy is indicated for the neoadjuvant treatment of resectable non-small cell lung cancer at high risk of recurrence in adult patients whose tumours have PD-L1 expression ≥1%
IND
Extension of indication to include OPDIVO for the treatment of patients with resectable stage II-IIIB non-small cell lung cancer
IND
Ociperlimab
Osimertinib
Osimertinib in combination with pemetrexed and platinum based chemotherapy for locally advanced (clinical stage IIIB, IIIC) or metastatic Non-Small Cell Lung Cancer (NSCLC) (clinical stage IVA or IVB) or recurrent Non-Small Cell Lung Cancer (NSCLC) not amenable to curative surgery or radiotherapy.
IND
Stage III unresectable Epidermal Growth Factor Receptor (EGFR) mutation positive non-small cell lung cancer (NSCLC)
IND
Extension of indication to include treatment of adult patients with locally advanced, unresectable (stage III) NSCLC whose tumours have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations and whose disease has not progressed during or following platinum-based chemoradiation therapy.
IND
Pembroliuzmab
IND
Pembrolizumab
KEYTRUDA as monotherapy is indicated for the adjuvant treatment of adults with non-small cell lung carcinoma who are at high risk of recurrence following complete resection and platinum‑based chemotherapy.
IND
Keytruda, in combination with platinum-containing chemotherapy as neoadjuvant treatment, and then continued as monotherapy as adjuvant treatment, is indicated for the treatment of resectable non‑small cell lung carcinoma at high risk of recurrence in adults
IND
Retifanlimab
IND
Sacituzumab Govitecan
IND
Serplulimab
Sugemalimab
Tiragolumab
In combination with atezolizumab for first line treatment of locally advanced, unresectable Stage III Non-small cell lung cancer in adults and elderly who have no progression during or following concurrent platinum-based chemoradiotherapy.
Tiragolumab in combination with Atezolizumab for first line treatment of locally advanced unresectable or metastatic high PD-L1, EGFR-negative, ALK-negative Non-small cell lung cancer in adults and elderly.
Tislelizumab
Tizveni as monotherapy is indicated for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer after prior platinum-based therapy. Patients with EGFR mutant or ALK positive NSCLC should also have received targeted therapies before receiving tislelizumab
Tizveni in combination with carboplatin and either paclitaxel or nab-paclitaxel is indicated for the first-line treatment of adult patients with squamous non-small cell lung cancer who have locally advanced NSCLC and are not candidates for surgical resection or platinum-based chemoradiation, or metastatic NSCLC
Tizveni in combination with pemetrexed and platinum‑containing chemotherapy is indicated for the first-line treatment of adult patients with non-squamous non-small cell lung cancer whose tumours have PD-L1 expression on ≥50% of tumour cells with no EGFR or ALK positive mutations and who have locally advanced NSCLC and are not candidates for surgical resection or platinum-based chemoradiation, or metastatic NSCLC
Extension of indication to include treatment of adult patients with non-small cell lung cancer (NSCLC) in combination and as monotherapy
IND
Toripalimab
IND
Trastuzumab deruxtecan
IND
Tremelimumab
Lung diseases other
Benralizumab
IND
Brensocatib
Gefapixant
Mometasone furoate sinus drug depot
Nintedanib
IND
Pamrevlumab
Sotatercept
Zinpentraxin alfa
Metabolic diseases
Afamelanotide
IND
Avalglucosidase alfa
Cipaglucosidase alfa
Dasiglucagon
IND
Eliglustat
IND
Elinzanetant
Encaleret
Fezolinetant
Govorestat
Patients with Classic Galactosaemia aged 2 to 65 years.
Sorbitol dehydrogenase deficiency
Leriglitazone
N-Acetyl-L-Leucine
Nedosiran
Olezarsen
Palopegteriparatide
Paltusotine
Pegunigalsidase alfa
RGX-121
Sepiapterin
Somapacitan
Sparsentan
Tiomolibdate choline
Multiple Myeloma
Ciltacabtagene autoleucel
IND
Daratumumab
IND
Elranatamab
Idecabtagene vicleucel
IND
Isatuximab
In Combination With Bortezomib, Lenalidomide and Dexamethasone (Isa VRd) in Patients With Newly Diagnosed Multiple Myeloma (NDMM) Not Eligible for Transplant.
IND
In combination with bortezomib, lenalidomide and dexamethasone (Isa VRd) in patients with newly diagnosed multiple myeloma (NDMM) eligible for transplant.
Pomalidomide
G
Selinexor
IND
Talquetamab
Teclistamab
Venetoclax
IND
Multiple sclerosis
Ublituximab
Muscular diseases other
Baclofen / naltrexone / sorbitol
Dantroleen
G
Daxibotulinumtoxine A
Deoxythymidine / deoxycytidine
Di-deuterated ethyl linoleate
Eculizumab
IND
Efgartigimod
Omaveloxolone
Rozanolixizumab
Satralizumab
IND
Zilucoplan
Myeloproliferative disorders
Avapritinib
IND
Momelotinib
Navitoclax
Pelabresib
Pemigatinib
IND
Neurological disorders other
Clazosentan
Deutetrabenazine (Extended release)
Eplontersen
Human normal immunoglobulin
IND
Nepla-tem-cel
Ravulizumab
IND
Satralizumab
Tiratricol
G
Tominersen
Trofinetide
Troriluzole
Oncology other
AL102
Afamitresgene autoleucel
Catequentinib
Efbemalenograstim alfa
Entrectinib
IND
Futibatinib
Melphalan hydrochloride
NY-ESO-1 autologous engineered TCR-T cells
Nirogacestat
Nivolumab
IND
Pembrolizumab
Indication for treatment in combination with gemcitabine and cisplatin, is indicated for the first-line treatment of locally advanced unresectable or metastatic biliary tract carcinoma in adults.
IND
Extension of indication to include in combination with pemetrexed and platinum chemotherapy the first -line treatment of adults and adolescents aged 12 years and older with unresectable advanced or metastatic malignant pleural mesothelioma.
IND
Repotrectinib
Retifanlimab
Patiënten met inoperabele, lokaal gevorderd of gemetastaseerd plaveiselcarcinoom van het anale kanaal.
Zynyz is indicated as monotherapy for the first‑line treatment of adult patients with metastatic or recurrent locally advanced Merkel cell carcinoma (MCC) not amenable to curative surgery or radiation therapy
Selinexor
IND
Sugemalimab
IND
Tebentafusp
Tislelizumab
Tevimbra as monotherapy is indicated for the treatment of adult patients with unresectable, locally advanced or metastatic oesophageal squamous cell carcinoma after prior platinum-based chemotherapy.
Extension of indication to include in combination with platinum-based chemotherapy the first-line treatment of adult patients with unresectable, locally advanced or metastatic oesophageal squamous cell carcinoma (OSCC)
Toripalimab
Toripalimab combined with cisplatin and gemcitabine for the first-line treatment of patients with locally recurrent or metastatic nasopharyngeal carcinoma (“NPC”)
Toripalimab combined with paclitaxel and cisplatin for the first-line treatment of patients with unresectable locally advanced/recurrent or metastatic esophageal squamous cell carcinoma (“ESCC”)
Other chronic immune diseases
Apremilast
IND
Arachis hypogaea (pinda) allergenen
IND
Atrasentan
Avapritinib
IND
Budesonide
IND
Coacillium topical
Dupilumab
Dupixent is geindiceerd voor de behandeling van eosinofiele oesofagitis in volwassenen, adolescenten en kinderen van 1 jaar en ouder, die ongecontroleerd zijn op, intolerant zijn voor, of die geen kandidaat zijn voor conventionele therapie.
IND
Extension of indication to include treatment of moderate to severe chronic spontaneous urticaria in adults and adolescents 12 years and older, who are symptomatic despite treatment with H1 antihistamines and who are intolerant to or inadequately controlled by anti-IgE therapy for Dupixent.
IND
Iptacopan
IND
Leniolisib
Lorecivivint
Marnetegragene autotemcel
Obinutuzumab
IND
Ritlecitinib
Sarilumab
IND
Sebetralstat
Teprotumumab
Other hematology
Lenzilumab
Obinutuzumab
IND
Other medication for cardiovascular diseases
Acoramidis
Aficamten
Bempedoic acid / ezetimibe
IND
Etripamil
Ferric carboxymaltose
Macitentan
IND
Macitentan / tadalafil
Mavacamten
Neoatricon (dopamine)
Omecamtiv mecarbil
Sotagliflozine
IND
Zalunfiban
Other metabolism and Endocrinology
Alpelisib
Autologous human chondrocytes in vitro expanded
C-type natriuretic peptide prodrug
Copper histidine
Linzagolix
IND
Pegzilarginase
Semaglutide
For weight management in people with obesity or who are overweight and have other related conditions.
Wegovy is indicated as an adjunct to a reduced-calorie diet and increased physical activity for weight management in adolescents ages 12 years and above with obesity and body weight above 60 kg. Treatment with Wegovy should be discontinued and re-evaluated if adolescent patients have not reduced their BMI by at least 5% after 12 weeks on the 2.4 mg or maximum tolerated dose.
IND
Extension of indication to include risk reduction of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established cardiovascular disease and BMI ≥27 kg/m2.
IND
Op dit moment heeft oraal semaglutide reeds een indicatie voor diabetes. De aan te vragen indicatie uitbreiding zal slaan op het behandelen van obesitas.
IND
Setmelanotide
IND
Setrusumab
Tirzepatide
IND
Vosoritide
IND
Other non-oncological hematological medications
Apadamtase alfa
Aprocitentan
Concizumab
Hemofilie A en B zonder inhibitors en een leeftijd van 12 jaar en ouder.
IND
Hemofilie A met inhibitors en hemofilie B met inhibitors, met een leeftijd van 12 jaar en ouder.
Crovalimab
Danicopan
Efanesoctocog alfa
IND
Exagamglogene autotemcel
Giroctocogene fitelparvovec
Hydroxycarbamide
IND
Iptacopan
Luspatercept
IND
Marstacimab
Mim 8
Mozafancogene autotemcel
Pegcetacoplan
IND
Pozelimab
Vadadustat
Ovarian cancer
Dostarlimab
IND
Mirvetuximab soravtansine
Olaparib
IND
Rucaparib
IND
Pancreatic cancer
Gemcitabine
Irinotecan in gepegyleerde liposomen
IND
Parasitic infections
Lotilaner
Prostate cancer
Aglatimagene besadenovec
Atezolizumab
IND
Degarelix
G
Enzalutamide
IND
Lutetium (177lu) vipivotide tetraxetan
Niraparib
IND
Niraparib / abirateron
Olaparib
IND
Radium-223
IND
Relugolix
Rucaparib
IND
Talazoparib
IND
Rheumatism
Bimekizumab
Bimzelx is indicated for the treatment of adults with active non-radiographic axial spondyloarthritis with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI) who have responded inadequately or are intolerant to non-steroidal anti-inflammatory drugs (NSAIDs), and for the treatment of adults with active ankylosing spondylitis who have responded inadequately or are intolerant to conventional therapy.
IND
Bimzelx, alone or in combination with methotrexate, is indicated for the treatment of active psoriatic arthritis in adults who have had an inadequate response or who have been intolerant to one or more disease-modifying antirheumatic drugs (DMARDs).
IND
Dapansutrile
Sarilumab
IND
SMA
Apitegromab
Risdiplam
IND
Schizophrenia, psychosis, bipolar disorder
Roluperidon
Xanomeline/ trospium
Skin cancer
Daromun
Ipilimumab
Extension of indication to include in combination with nivolumab the treatment of adolescents (12 years of age and older) for advanced (unresectable or metastatic) melanoma.
IND
Neoadjuvant Ipilimumab Plus Nivolumab in Macroscopic Stage III Melanoma.
IND
Lifileucel
Nivolumab/relatlimab/hyaluronidase Ph20
Relatlimab / nivolumab
Tucidinostat
Skin diseases
Abrocitinib
IND
Beremagene geperpavec
Bimekizumab
IND
Clascoterone
Concentrate of proteolytic enzymes enriched in bromelain
IND
Delgocitinib
Deucravacitinib
Glycopyrronium
IND
Lebrikizumab
Methotrexaat
IND
Nemolizumab
Piclidenoson
Prademagene zamikeracel
Remibrutinib
Rocatinlimab
Roflumilast topicaal
Secukinumab
IND
Spesolimab
IND
Stem cell transplants
Abatacept
IND
ECT-001-CB
Nomacopan
Treosulfan
IND
Stomach cancer
Catumaxomab
Domvanalimab
Pembrolizumab
Extension of indication for treatment with pembrolizumab plus trastuzumab in combination with standard of care chemotherapy for adults with HER2 positive Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
IND
Treatment in the neoadjuvant or adjuvant setting of previously untreated adults with gastric and gastroesophageal junction (GEJ) adenocarcinoma.
IND
Tislelizumab
IND
Trastuzumab deruxtecan
IND
Zolbetuximab
Thyroid cancer
Selpercatinib
IND
Tumour agnostic medication
MDM2-p53 antagonist
Selpercatinib
IND
Trastuzumab Deruxtecan
IND
Unknown
ARINA-1
Apremilast
G
Belzutifan
Bulevirtide
Colistimethate Sodium
IND
Decitabine / cedazuridine
IND
Mirabegron
IND
Molgramostim
IND
Mycofenolaatmofetil
IND
Olezarsen
Pegcetacoplan
IND
Pembrolizumab
IND
Pitavastatine
Relugolix / estradiol / norethisterone acetaat
IND
Vibegron
Viral infections other
Bulevirtide
Clesrovimab
IND
Letermovir
Extension of indication to include treatment of prophylaxis of CMV disease in CMV-seronegative adults who have received a kidney transplant from a CMV-seropositive donor [D+/R-].
G
Extension of Letermovir From Day 100 to Day 200 Post-transplant for the Prevention of Cytomegalovirus Infection in Hematopoietic Stem Cell Transplant.
IND
Nirsevimab
IND
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